Beilstein J. Org. Chem.2015,11, 994–999, doi:10.3762/bjoc.11.111
from Pd2dba3 and 3-methylbenzothiazolium salt V as precursors. A comparison of the performance of benzothiazole carbene with phosphanes and an analogous imidazolium carbene ligand is also proposed.
Keywords: active methylene compounds; allylic carbonates; Pd–benzothiazol-2-ylidenecomplex; Tsuji–Trost
allylic alkylation of nucleophiles [30][31][32][33][34][35][36].
Some years ago, we synthesized the first example of Pd–benzothiazol-2-ylidenecomplex I (Figure 1), which proved to be an efficient catalyst for several C–C coupling reactions (like carbonylations and Heck olefinations) carried out in both
-2-ylidenecomplex I was found to be a chemoselective catalyst for the Tsuji–Trost allylation of active methylene compounds carried out under neutral conditions and using carbonates as allylating agents. The proposed protocol consists in a simplified procedure adopting an in situ prepared catalyst